Hydrochloride methanol → HCID 68999927, compound

HRID 1821338Notes

Reaction equation

HRID 1821338 reaction equation
[CH3:1][N:2]([CH3:31])[C:3]([C:5]1[CH:6]=[CH:7][C:8](/[CH:20]=[CH:21]/[C:22]2[C:30]3[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=3)[NH:24][N:23]=2)=[C:9]([NH:11][C:12]([C:14]2[S:15][CH:16]=[CH:17][C:18]=2[CH3:19])=[O:13])[CH:10]=1)=[O:4].[ClH:32].CO>CO>[ClH:32].[CH3:31][N:2]([CH3:1])[C:3]([C:5]1[CH:6]=[CH:7][C:8](/[CH:20]=[CH:21]/[C:22]2[C:30]3[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=3)[NH:24][N:23]=2)=[C:9]([NH:11][C:12]([C:14]2[S:15][CH:16]=[CH:17][C:18]=2[CH3:19])=[O:13])[CH:10]=1)=[O:4]

Participants

4

Reactant 2

HCID 21893726Hydrochloride methanolHCID 68999928HCID 68999928, compound

Product 1

HCID 68999927HCID 68999927, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a similar manner to Example 115, Compound 125 (360 mg, 78%) was obtained from Compound 117, methanol (6.0 mL) and 4 mol/L hydrogen chloride-methanol solution (2.0 mL).

Sources & evidence

ORD record
ord-e1e6bf0aa41f499ab2576c533ae3dc38
Source dataset
uspto-grants-2009_10
Patent number
US07605272B2

Reaction notes

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