Water → HCID 68999122, compound

Participants

Reaction Steps

Compound 167 (38 mg, 0.16 mmol) was dissolved in methanol (2.0 mL) and added with sodium borohydride (12 mg, 0.32 mmol) followed by stirring at room temperature for 4 hours. The reaction mixture was added with water, extracted with ethyl acetate and the organic layer was concentrated. Then, the residue was triturated in ethyl acetate to obtain Compound 168 (23 mg, 45%).

Provenance & Evidence