Dimethylformamide → HCID 86628225, compound

Participants

Reaction Steps

In a similar manner to Example 29, 3-methylbenzo[b]thiophene-2-carboxylic acid (0.14 g, 0.70 mmol) was treated with thionyl chloride (79 μL, 1.1 mmol), DMF (7.4 μL, 0.13 mmol) and dichloromethane (3.0 mL), followed by reacting with Compound 2 (0.15 g, 0.64 mmol), triethylamine (0.23 mL, 1.6 mmol) and THF (3.0 mL) to obtain Compound 351 (261 mg, 100%).

Provenance & Evidence