HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfide → HCID 178482982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfide | HCID 1068 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 178482983 | HCID 178482983 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178482982 | HCID 178482982 | — |
Reaction Steps
Compound 30 (0.45 g, 0.37 mmol) was treated with 20 ml of a cleavage cocktail (10:10:1:1 TFA:CH2Cl2: Me2S: H2O). After one hour, the solvent was removed and the residue purified by RPHPLC. Fractions containing the product were combined, concentrated to a small volume and lyophilized to yield a yellow solid (0.23 g, 0.18 mmol, 49%, compound 32).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605175B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-6d7964baaf0e45b1ab3cc37da22317a8 |
| Source note | uspto-grants-2009_10 |