HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Carbobenzoxy-L-valine → (S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Carbobenzoxy-L-valine | HCID 726987 | — |
| Reactant | Methyl L-prolinate | HCID 853477 | — |
| Product | (S)-Methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylate | HCID 14032133 | — |
Reaction Steps
Z-Val-OH (3.5 g, 13.9 mmol) and H-Pro-OMe*HCl (2.14 g, 13.9 mmol) were treated in the same manner as above for 1, to give 3 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608577B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-89169db16151430b8337a1288128f478 |
| Source note | uspto-grants-2009_10 |