反应详情

1 eq of Boc-Ala-Val-OH or Boc-Ala-Gly-OH and 0.9 eq of 36 or 37, 1.1 eq of HOBt, and 1.1 eq of WSCD were dissolved in dry ACN. After addition of 0.9 eq of TEA the mixture was stirred overnight. The solvent was removed and the remaining oil was dissolved in ethyl acetate. The solution was washed with brine and dried.

1. customThe solvent was removed
2. dissolutionthe remaining oil was dissolved in ethyl acetate
3. washThe solution was washed with brine
4. customdried