HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → 2-[(Benzothiazol-2-yl)carbonyl]-1-{N-[N-(tertbutyloxycarbonyl)-(L)-Alanyl]-glycyl}-(2S)-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-[(Benzothiazol-2-yl)hydroxymethyl]-1-{N-[N-(tertbutyloxycarbonyl) (L)-Alanyl]-glycyl}-(2S)-pyrrolidin | HCID 69032265 | — |
| Product | 2-[(Benzothiazol-2-yl)carbonyl]-1-{N-[N-(tertbutyloxycarbonyl)-(L)-Alanyl]-glycyl}-(2S)-pyrrolidine | HCID 69031113 | — |
Reaction Steps
40 (0.62 g, 0.134 mmol), oxalylchloride (0.207 ml, 2.41 mmol), DMSO (2.37 ml, 3.35 mmol), TEA (0.75 ml, 5.35 mmol)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608577B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-ef8781b30cda46578557c23d04296d33 |
| Source note | uspto-grants-2009_10 |