hydroxylamine-O-sulfonic acid → 1,3-Benzenedicarbonitrile, 4-fluoro-

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-fluoro-5-formylbenzonitrile (5.1 g, 33.9 mmol) in water (75 ml) was added hydroxylamine-O-sulphonic acid (4.6 g, 40.7 mmol) and the reaction mixture was heated at 50° C. for 5 h. The mixture was filtered and the solid material was washed with water and dried in vacuo for 18 h to give the title compound (4.3 g)

Provenance & Evidence