1,2,3,4-Tetrahydroisoquinoline → HCID 58933897, compound

HRID 1821612Notes

Reaction equation

HRID 1821612 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([OH:14])=O)[CH:6]=[CH:5]2.[CH2:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:18][CH2:17][NH:16]1>>[CH2:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:18][CH2:17][N:16]1[C:12]([C:7]1[CH:6]=[CH:5][C:4]2[C:9](=[CH:10][CH:11]=[C:2]([OH:1])[CH:3]=2)[CH:8]=1)=[O:14]

Participants

3

Procedure

The title compound was synthesised from 6-hydroxy-2-naphtoic acid (commercially available) and 1,2,3,4-tetrahydroisochinoline (commercially available) according to the procedure described for Example A. MS (m/e): 302.1 (MH−, 100%)

Sources & evidence

ORD record
ord-aa54e713480446e48529075d60787195
Source dataset
uspto-grants-2009_10
Patent number
US07608617B2

Reaction notes

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