P-Anisidine → HCID 1514834, compound

HRID 1821627Notes

Reaction equation

HRID 1821627 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[N:14]=[C:13](Cl)[N:12]=[C:11]([Cl:16])[N:10]=2)=[CH:4][CH:3]=1.[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([NH2:25])=[CH:21][CH:20]=1>>[Cl:16][C:11]1[N:10]=[C:9]([NH:8][C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=2)[N:14]=[C:13]([NH:25][C:22]2[CH:23]=[CH:24][C:19]([O:18][CH3:17])=[CH:20][CH:21]=2)[N:12]=1

Participants

3

Reactant 2

HCID 7732P-AnisidineHCID 167632272-29-9

Product 1

HCID 1514834HCID 1514834, compoundYield 62%

Procedure

The reaction of (4-chloro-phenyl)-(4,6-dichloro-[1,3,5]triazin-2-yl)-amine with p-anisidine, according to method 2, gave 6-chloro-N-(4-chlorophenyl)-N′-(4-methoxyphenyl)-[1,3,5]triazine-2,4-diamine (51 mg, 62%): 1H NMR (CDCl3) 7.21-7.50 (6H, m), 6.91(2H, d, J=11 Hz), 3.85 (3H, s).

Sources & evidence

ORD record
ord-847b6d1cffe143c38d271e1f6eabc6e3
Source dataset
uspto-grants-2009_10
Patent number
US07608620B2

Reaction notes

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