HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl isoleucinate--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | L-Isoleucine | HCID 6306 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Ethyl isoleucinate--hydrogen chloride (1/1) | HCID 6453390 | — |
Reaction Steps
L-isoleucine ethyl ester hydrochloride salt was prepared by the procedure in Example 1(B) utilizing L-isoleucine (5.0 g, 38.1 mmol), thionyl chloride (8.3 mL, 11.44 mmol) and EtOH (33.54 mL, 57.15 mmol). The ethyl ester 14t was obtained as a colorless oil (2.5 g, 14.91 mmol, 39%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608599B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-912772c555084e3bbdf7db179746057a |
| Source note | uspto-grants-2009_10 |