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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1821889Generated: October 31, 2026

phenyl(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone → tert-Butyl 3-[[[phenyl(1H-pyrrolo[2,3-c]pyridin-2-yl)methylene]amino]oxy]piperidine-1-carboxylate

https://huagongshe.com/reaction/1821889

Reaction equation

Participants

RoleNameHCIDCharge
Reactantphenyl(1H-pyrrolo[2,3-c]pyridin-2-yl)methanoneHCID 57893467—
ReactantTert-butyl 3-(aminooxy)piperidine-1-carboxylateHCID 68983062—
Producttert-Butyl 3-[[[phenyl(1H-pyrrolo[2,3-c]pyridin-2-yl)methylene]amino]oxy]piperidine-1-carboxylateHCID 136366047—

Reaction Steps

tert-Butyl 3-[[[phenyl(1H-pyrrolo[2,3-c]pyridin-2-yl)methylene]amino]oxy]piperidine-1-carboxylate was prepared from phenyl(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone (Example 35) and tert-butyl 3-(aminooxy)piperidine-1-carboxylate (Reference Example 11) following the procedure described for Example 104 (geometry of the oxime double bond undefined).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07608627B2
Source datasetuspto-grants-2009_10
ORD IDord-4a4957f18c3847b5ba175f8c1528ea6f
Source noteuspto-grants-2009_10