tert-butyl N-(2-(aminooxy)ethyl)carbamate → HCID 136366089, compound

Participants

Reaction Steps

tert-Butyl 2-[[[(4-chlorophenyl)(1H-pyrrolo[2,3-c]pyridin-2-yl)methylene]amino]oxy]ethylcarbamate was prepared from (4-chlorophenyl)(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone (Example 103) and tert-butyl[2-(aminooxy)ethyl]carbamate following the procedure described for Example 104. Purification by Biotage chromatography (silica, 2 to 15% methanol in methylene chloride) provided tert-butyl 2-[[[(4-chlorophenyl)(1H-pyrrolo[2,3-c]pyridin-2-yl)methylene]amino]oxy]ethylcarbamate (geometry of the oxime double bond undefined).

Provenance & Evidence