反应详情

温度

45 °C

A 250 ml round-bottomed flask fitted with a condenser, nitrogen purge, and addition funnel was charged with 29.9 g (0.3 mol) 2-cyclohexen-1-one and heated to 45° C. with stirring. Di-(iso-butyl)phosphine (28.8 g, 0.2 mol) was gradually added to the flask via the addition funnel, over a period of 0.5 hour. When addition was complete, the temperature of the contents of the flask was slowly raised to 70° C. and maintained at that temperature for 3 hours, then cooled. Unreacted starting materials were removed by evaporation under reduced pressure at 120° C.

1. customA 250 ml round-bottomed flask fitted with a condenser
2. customnitrogen purge
3. additionaddition funnel
4. additionWhen addition
5. temperaturethe temperature of the contents of the flask was slowly raised to 70° C.
6. temperaturemaintained at that temperature for 3 hours
7. temperaturecooled
8. customwere removed by evaporation under reduced pressure at 120° C.