HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridineacetic acid, hydrochloride (1:1) → 3-Pyridineacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridineacetic acid, hydrochloride (1:1) | HCID 2723724 | — |
| Reactant | Potassium hydroxide ethanol | HCID 21946426 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Pyridineacetic acid | HCID 108 | 102.2% |
Reaction Steps
To a suspension of 2-(pyridin-3-yl)acetic acid-hydrochloride (13.2 g, 75.6 mmol) in ethanol (100 mL) was added a solution (150 mL) of 0.5 mol potassium hydroxide/ethanol, and the mixture was stirred well, then filtered to remove potassium chloride, concentrated, and dried to give 2-(pyridin-3-yl)acetic acid (10.6 g, quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608716B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-f8cdf3a673944154833564b490d46a02 |
| Source note | uspto-grants-2009_10 |