Chlorohydroxy benzophenone → HCID 11260295, compound

HRID 1822261Notes

Reaction equation

HRID 1822261 reaction equation
C[O:2][C:3](=[O:21])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15](Br)[CH:14]=2)=[CH:8][C:7]=1[CH3:20].[Cl:22][C:23]1[CH:24]=[CH:25][C:26]([OH:37])=[C:27]([C:29]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)=[O:30])[CH:28]=1>>[C:29]([C:27]1[CH:28]=[C:23]([Cl:22])[CH:24]=[CH:25][C:26]=1[O:37][C:15]1[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=1)[O:12][C:9]1[CH:10]=[CH:11][C:6]([CH2:5][CH2:4][C:3]([OH:2])=[O:21])=[C:7]([CH3:20])[CH:8]=1)(=[O:30])[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

Participants

3

Reactant 2

HCID 6799Chlorohydroxy benzophenoneHCID 578941923-[4-(3-Bromo-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester

Product 1

HCID 11260295HCID 11260295, compound

Procedure

The title compound is prepared by reacting the compound of 3-[4-(3-bromo-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester with (5-chloro-2-hydroxy-phenyl)-phenyl-methanone as in Example 18 to afford 0.080 g. 1H NMR (400 MHz, CDCl3); MS (ES+) m/z mass calculated for C29H23O5Cl 486, found 487 and 489 (M+1 and M+3, 100%).

Workup

  1. customto afford 0.080 g

Sources & evidence

ORD record
ord-6d9b98e5fe9943c1b5910abd2107397a
Source dataset
uspto-grants-2009_10
Patent number
US07608639B2

Reaction notes

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