2'-Hydroxybenzophenone → HCID 11247971, compound

HRID 1822264Notes

Reaction equation

HRID 1822264 reaction equation
C[O:2][C:3](=[O:21])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15](Br)[CH:14]=2)=[CH:8][C:7]=1[CH3:20].[OH:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[C:29]([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)=[O:30]>>[C:29]([C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=1[O:22][C:15]1[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=1)[O:12][C:9]1[CH:10]=[CH:11][C:6]([CH2:5][CH2:4][C:3]([OH:2])=[O:21])=[C:7]([CH3:20])[CH:8]=1)(=[O:30])[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

Participants

3

Reactant 2

HCID 83482'-HydroxybenzophenoneHCID 578941923-[4-(3-Bromo-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester

Product 1

HCID 11247971HCID 11247971, compound

Procedure

The title compound is prepared by reacting the compound of 3-[4-(3-bromo-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester with (2-hydroxy-phenyl)-phenyl-methanone as in Example 18 to afford 0.020 g (14%). 1H NMR (400 MHz, CDCl3); HRMS (ES+) m/z mass calculated for C29H24O5 453.1702, found 453.1699.

Workup

  1. customto afford 0.020 g (14%)

Sources & evidence

ORD record
ord-a7e3644f3ec94bc7867b29b1a5cfd9c2
Source dataset
uspto-grants-2009_10
Patent number
US07608639B2

Reaction notes

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