HRID1822271

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID57894233

未命名化合物

HCID58753926

未命名化合物

PRODUCTS

生成物

结构：CCc1ccc(Oc2cc(F)cc(Oc3ccc(CCC(=O)O)c(C)c3)c2)c(C(C)(C)c2ccccc2)c1

HCID11179800

未命名化合物

PROCEDURE

实验过程

The title compound is prepared by reacting the compound of 3-[4-(3-bromo-5-fluoro-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester with 4-ethyl-2-(1-methyl-1-phenyl-ethyl)-phenol as in Example 18 to afford 0.027 g (10%). 1H NMR (400 MHz, CDCl3); MS (ES+) m/z mass calculated for C33H33O4F 512, found 513 (M+1, 100%).

WORKUP

后处理

customto afford 0.027 g (10%)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7ef7e646d53c4a03870af8712aeca37a
来源数据集: uspto-grants-2009_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07608639B2
来源说明: uspto-grants-2009_10

反应 SMILES

C[O:2][C:3](=[O:22])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:18]=[C:17]([F:19])[CH:16]=[C:15](Br)[CH:14]=2)=[CH:8][C:7]=1[CH3:21].[CH2:23]([C:25]1[CH:30]=[CH:29][C:28]([OH:31])=[C:27]([C:32]([CH3:40])([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH3:33])[CH:26]=1)[CH3:24]>>[CH2:23]([C:25]1[CH:30]=[CH:29][C:28]([O:31][C:15]2[CH:14]=[C:13]([CH:18]=[C:17]([F:19])[CH:16]=2)[O:12][C:9]2[CH:10]=[CH:11][C:6]([CH2:5][CH2:4][C:3]([OH:2])=[O:22])=[C:7]([CH3:21])[CH:8]=2)=[C:27]([C:32]([CH3:33])([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH3:40])[CH:26]=1)[CH3:24]