HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorohydroxy benzophenone → 3-{4-[3-(2-Benzoyl-4-chloro-phenoxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorohydroxy benzophenone | HCID 6799 | — |
| Reactant | 3-[4-(3-Bromo-5-methyl-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester | HCID 57894212 | — |
| Product | 3-{4-[3-(2-Benzoyl-4-chloro-phenoxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid | HCID 11477576 | — |
Reaction Steps
The title compound is prepared by reacting the compound of 3-[4-(3-bromo-5-methyl-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester with (5-chloro-2-hydroxy-phenyl)-phenyl-methanone as in Example 18 to afford 0.244 g (38%). 1H NMR (400 MHz, CDCl3); HRMS (ES+) m/z exact mass calculated for C30H25O5Cl 501.1469, found 501.1474.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608639B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-12f5079042f54f2d8af845da03de3553 |
| Source note | uspto-grants-2009_10 |