HCID 57894173, compound → HCID 11477969, compound

HRID 1822297Notes

Reaction equation

HRID 1822297 reaction equation
C([O:3][C:4](=[O:34])[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([O:21][C:22]3[CH:27]=[CH:26][C:25]([C:28]([F:31])([F:30])[F:29])=[CH:24][C:23]=3Br)[CH:15]=2)=[CH:9][C:8]=1[CH3:33])C.[OH:35][C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][N:37]=1>>[CH3:33][C:8]1[CH:9]=[C:10]([O:13][C:14]2[CH:15]=[C:16]([O:21][C:22]3[CH:27]=[CH:26][C:25]([C:28]([F:29])([F:30])[F:31])=[CH:24][C:23]=3[N:37]3[CH:38]=[CH:39][CH:40]=[CH:41][C:36]3=[O:35])[CH:17]=[C:18]([CH3:20])[CH:19]=2)[CH:11]=[CH:12][C:7]=1[CH2:6][CH2:5][C:4]([OH:3])=[O:34]

Participants

3

Reactant 2

HCID 57894173HCID 57894173, compoundHCID 178516071HCID 178516071, compound

Product 1

HCID 11477969HCID 11477969, compound

Procedure

The title compound is prepared by reacting the compound of 3-{4-[3-(2-bromo-4-trifluoromethyl-phenoxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid ethyl ester with 2-hydroxypyridine as in Example 45 to afford 0.010 g (8%). 1H NMR (400 MHz, CDCl3); MS (ES+) m/z mass calculated for C29H24NO5F3 523, found 524 (M+1, 100%).

Workup

  1. customto afford 0.010 g (8%)

Sources & evidence

ORD record
ord-b963ca1ae6d64884ace800e9e5268260
Source dataset
uspto-grants-2009_10
Patent number
US07608639B2

Reaction notes

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