HCID 57894198, compound → HCID 57894137, compound

Participants

Reaction Steps

A mixture of 3-[4-(3-benzyloxy-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester (10.54 g, 28.0 mmol) and 10% Pd/C (5 g) in ethyl acetate (150 mL) is purged with N2 and then H2. The mixture is stirred under a hydrogen balloon. Upon completion, the mixture is filtered through hyflo, and the solvent is removed in vacuo to afford 8.18 g (100%) of the titled compound. Rf=0.59 (4/1 hexanes/EtOAc). 1H NMR (400 MHz, CDCl3); MS (ES+) m/z mass calcd for C17H18O4 286, found 287 (M+1, 100%).

Provenance & Evidence