Neopentyl glycol → 2-(5-Chlorothiophen-2-yl)-5,5-dimethyl-[1,3,2]dioxaborinane

HRID 1822646Notes

Reaction equation

[Cl:1][C:2]1[S:6][C:5]([B:7]([OH:9])[OH:8])=[CH:4][CH:3]=1.[CH3:10][C:11]([CH2:15]O)([CH2:13]O)[CH3:12]>>[Cl:1][C:2]1[S:6][C:5]([B:7]2[O:9][CH2:12][C:11]([CH3:15])([CH3:13])[CH2:10][O:8]2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 31344Neopentyl glycol

HCID 27343245-Chlorothiophene-2-boronic acid

Product 1

HCID 103989832-(5-Chlorothiophen-2-yl)-5,5-dimethyl-[1,3,2]dioxaborinaneYield 54%

Procedure

The title compound (54%, crystals) was prepared from 5-chlorothiophen-2-boronic acid and neopentylglycol.

Sources & evidence

ORD record: ord-651969cc53834ff6ad060babc37b3893
Source dataset: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07037905B2

Reaction notes

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