Acetyl chloride → HCID 86592163, compound

HRID 1822766Notes

Reaction equation

HRID 1822766 reaction equation
[CH2:1]([NH:5][C:6](=[O:20])[C@H:7]([CH2:16][CH2:17][CH2:18][CH3:19])[NH:8]C(OC(C)(C)C)=O)[CH2:2][CH2:3][CH3:4].C([Cl:24])(=O)C>CO>[ClH:24].[CH2:1]([NH:5][C:6](=[O:20])[C@H:7]([CH2:16][CH2:17][CH2:18][CH3:19])[NH2:8])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 23568573HCID 23568573, compound

Product 1

HCID 86592163HCID 86592163, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The N-Boc-L-norleucine butylamide in methanol is treated with acetyl chloride. After 45 minutes, all volatiles are removed under reduced pressure to yield L-norleucine butylamide hydrochloride.

Workup

  1. customall volatiles are removed under reduced pressure

Sources & evidence

ORD record
ord-a6588bcb06a14b788b5321fb6eddd82b
Source dataset
uspto-grants-2006_05
Patent number
US07037916B2

Reaction notes

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