HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Ethoxymethylene)propanedinitrile → HCID 178505471, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Ethoxymethylene)propanedinitrile | HCID 67152 | — |
| Reactant | 4-Fluorobenzene-1,2-diamine | HCID 164584 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 178505471 | HCID 178505471 | 83.4% |
Reaction Steps
A solution of 4-fluoro-1,2-phenylenediamine (2.0 g) and ethoxymethylenemalononitrile (2.9 g) in isopropanol (80 mL) was heated to reflux overnight. The volatiles were removed in vacuo to yield 5-fluoro-1H-benzimidazole (1.8 g). ESI-MS (m/z) 137 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037916B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-76668b795070455db6c49f3c41266b69 |
| Source note | uspto-grants-2006_05 |