HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dibromopropane → HCID 10200722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dibromopropane | HCID 8001 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 135788285 | HCID 135788285 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 10200722 | HCID 10200722 | 9% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 4-(2-ethylanilino)-7-hydroxy-6-methoxy-3-quinolinecarboxamide (0.12 g, 0.35 mmol), DMSO (15 ml), Cs2CO3 (0.34 g, 1.0 mmol), and 1,3-dibromopropane was stirred at 100° C. for 2 h. The reaction mixture was poured out on NaHCO3 (aq) and extracted with CH2Cl2. The substance was chromatographed on furnishing the title compound (0.012 g, 9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037925B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-6dee1f6ad89d40ab88ca7b4e57831763 |
| Source note | uspto-grants-2006_05 |