Ammonia → HCID 10269112, compound

HRID 1822860Notes

Reaction equation

HRID 1822860 reaction equation
C([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[CH3:23])=[CH:13][C:12]([Cl:24])=[C:11]([Cl:25])[CH:10]=2)=O)C.[NH4+:26].[Cl-].N>>[Cl:24][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][C:11]=1[Cl:25])[N:8]=[CH:7][C:6]([C:4]([NH2:26])=[O:3])=[C:15]2[NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[CH3:23]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 22170251HCID 22170251, compound

Product 1

HCID 10269112HCID 10269112, compound

Procedure

A mixture of Ethyl-6,7-dichloro-4-(2-methylanilino)-3-quinolinecarboxylate (0.050 g, mmol) and NH4Cl was heated in a pressure vessel with NH3-saturated methanol for five days. The mixture was evaporated and the residue was recrystallized from EtOH.

Workup

  1. customThe mixture was evaporated
  2. customthe residue was recrystallized from EtOH

Sources & evidence

ORD record
ord-4668b47aa7054832b361dd1c719da3aa
Source dataset
uspto-grants-2006_05
Patent number
US07037925B2

Reaction notes

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