HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-methyl-3-nitrobenzyl)-1-ethanamine → 3-[(Ethylamino)methyl]-2-methylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-methyl-3-nitrobenzyl)-1-ethanamine | HCID 22170308 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol ethylacetate | HCID 21584252 | — |
| Product | 3-[(Ethylamino)methyl]-2-methylaniline | HCID 22170256 | 98.7% |
Reaction Steps
N-(2-methyl-3-nitrobenzyl)-1-ethanamine (0.46 g, 2.3 mmol) was hydrogenated over 5% palladium-charcoal 80 mg in EtOAc/EtOH 1:1 (14 ml) for four hours. The mixture was filtered through celite, and the filtrate was concentrated to give the title compound 0.373 g (97%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037925B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-6d4ae3ae76904c4e9469c226600f0dc3 |
| Source note | uspto-grants-2006_05 |