HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 22170798, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Carbamic acid, (5-formyl-2-thiazolyl)-, phenylmethyl ester | HCID 22170759 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22170798 | HCID 22170798 | 71% |
Reaction Steps
530 mg (14 mmol) of sodium borohydride were added in small portions to a stirred solution of 7 g (27 mmol) of 2-benzyloxycarbonylamino-5-formyl-1,3-thiazole in 80 ml of methanol at room temperature. The reaction went on for 2 hours. After evaporation of the solvent the residue was purified by chromatography (cyclohexane-ethylacetate) to give 5.05 g (71% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037929B1 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-5b4cdfb7bc194704b9f2c8be00292658 |
| Source note | uspto-grants-2006_05 |