HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,4-Trichloro-5-methoxy-1,3-dihydro-indol-2-one → 4-chloro-5-methoxy-1H-indole-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,4-Trichloro-5-methoxy-1,3-dihydro-indol-2-one | HCID 22169677 | — |
| Reactant | Methanol--water (1/1) | HCID 22242641 | — |
| Product | 4-chloro-5-methoxy-1H-indole-2,3-dione | HCID 14595059 | — |
Reaction Steps
Hydrolysis of 3,3,4-trichloro-5-methoxy-1,3-dihydro-indol-2-one in MeOH-water mixture according to the procedure published in Tetrahedron 27, 3263-70 (1971) provided 4-chloro-5-methoxy-1H-indole-2,3-dione as a deep-brown shiny crystals in 96% Y.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037909B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-47faadbdac5e454289bdecaf4c77c51d |
| Source note | uspto-grants-2006_05 |