HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-7-methyl isatin → 5-Chloro-3-(4-fluoro-benzyl)-8-methyl-9H-1,2,3a,4,9,10-hexaazacyclopenta[b]fluorene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-7-methyl isatin | HCID 1810509 | — |
| Reactant | 5-[(4-Fluorophenyl)methyl]-4H-1,2,4-triazole-3,4-diamine | HCID 21919322 | — |
| Product | 5-Chloro-3-(4-fluoro-benzyl)-8-methyl-9H-1,2,3a,4,9,10-hexaazacyclopenta[b]fluorene | HCID 135454845 | — |
Reaction Steps
According to the general cyclization procedure (for Example 27), 0.60 mmol of 4-chloro-7-methyl-1H-indole-2,3-dione (117.5 mg) and 0.70 mmol of 5-(4-fluoro-benzyl)-[1,2,4]triazole-3,4-diamine (145 mg) was used for the preparation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037909B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-30276b5c0a0f4086ab85220bc9691d52 |
| Source note | uspto-grants-2006_05 |