HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-7-methyl isatin → 4-(5-Chloro-8-methyl-9H-1,2,3a,4,9,10-hexaaza-cyclopenta[b]fluoren-3-ylmethyl)-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-7-methyl isatin | HCID 1810509 | — |
| Reactant | 4-[(4,5-Diamino-4H-1,2,4-triazol-3-yl)methyl]phenol | HCID 21919313 | — |
| Product | 4-(5-Chloro-8-methyl-9H-1,2,3a,4,9,10-hexaaza-cyclopenta[b]fluoren-3-ylmethyl)-phenol | HCID 135537650 | — |
Reaction Steps
According to the general cyclization procedure (for Example 27), 0.60 mmol of 4-chloro-7-methyl-1H-indole-2,3-dione (117.5 mg) and 0.70 mmol of 4-(4,5-diamino-4H-[1,2,4]triazol-3-ylmethyl)-phenol (144 mg) was used for the preparation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037909B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-c797d0bf6927468c8b7840d6c7cf44d5 |
| Source note | uspto-grants-2006_05 |