Acetic Anhydride → HCID 11361213, compound

Participants

Reaction Steps

The product from Example 3 (150 mg, 0.435 mmol) in acetic anhydride (0.24 mL, 2.54 mmol) was heated in tetrahydrofuran (2 mL) at 40° C. overnight. The mixture was allowed to cool to room temperature and concentrated under reduced pressure to provide the title compound as a solid. 1H NMR (300 MHz, DMSO-d6) δ 10.25 (s, 1H), 9.68 (s, 1H), 8.53 (dd, J=4.6 Hz, 1.5 Hz, 1H), 8.06 (m, 2H), 7.91 (dd, J=8.1 Hz, 1.3 Hz, 1H), 7.7–7.78 (m, 4H), 7.36–7.45 (m, 3H), 1.97 (s, 3H), 1.29 (s, 9H); MS (ESI30 ) m/z 388 (M+H)+.

Provenance & Evidence