反应详情

To a solution of 7-benzyloxy-1methyl-1H-indole in 20 mL of ethanol was added 10% palladium on charcoal (0.2 g). This solution was stirred under balloon pressure hydrogen atmosphere for 4 h, then filtered through celite and concentrated in vacuo. This material was purified by flash chromatography, eluting silica gel with hexane:ethyl acetate (100:0 to 50:50) to give the product (0.58 g, 87%); Mass spectrum (TOF): m/z=147.1 (M).

1. filtrationfiltered through celite and
2. concentrationconcentrated in vacuo
3. customThis material was purified by flash chromatography
4. washeluting silica gel with hexane:ethyl acetate (100:0 to 50:50)