Hydrochloric Acid → HCID 9985454, compound

Participants

Reaction Steps

To a solution the compound (54 mg, 0.085 mmol) obtained from Step G was added HCl in dioxane (4.0 M, 0.38 mL, 1.5 mmol) and 2 drops of methanol. The mixture was stirred at rt overnight. Solvent was removed to give a white solid as product in quantitative yield. 1HNMR (300 MHz, CDOD3) δ 9.35 (s, 2H), 9.07 (s, 2H), 7.80 (d, 2H, J=8.5 Hz), 7.47 (d, 2H, J=6.6 Hz), 7.30–7.16 (m, 5H), 4.96 (t, 1H, J=7.3 Hz), 4.42–4.23 (m, 3H), 3.24 (m, 1H), 2.60 (m, 2H), 2.2–1.6 (m, 12H). MS m/e 533.4 (M+H).

Provenance & Evidence