Trifluoroacetic acid → HCID 10345915, compound

Participants

Reaction Steps

The compound (22 mg, 0.116 mmol) obtained from Step E was dissolved in CH2Cl2 and treated with TFA (180 μL, 2.32 mmol). Let stir 2 h at room temperature. Concentrated under vacuum, lyopholized to give a white solid (18 mg). 1HNMR (300 MHz, CD3OD) δ 2.49 (s, 3H) 3.2–3.4 (m, 2H) 4.6–4.9 (m, 2H) 5.2 (m, 1H), 5.25 (s, 2H) 7.3–7.5 (m, 9H), 7.6 (m, 2H) 7.8 (m, 2H). MS m/e 502.4 [M+H].

Provenance & Evidence