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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18233Generated: October 26, 2026

1,3-dimethyl-1H-indole-2-carbaldehyde → methyl({1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}methyl)amine

https://huagongshe.com/reaction/18233

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-dimethyl-1H-indole-2-carbaldehydeHCID 2771468—
Reactant1-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehydeHCID 10441960—
Productmethyl({1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}methyl)amineHCID 2213904445%

Reaction Steps

According to the procedure of Preparation 13 (c), except substituting 1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde (0.4 g, 2.5 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.2 g, 45%) was prepared as a yellow oil: MS (ES) m/e 176 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741339B2
Source datasetuspto-grants-2010_06
ORD IDord-19d61b4c1c814dddbb8d948148342423
Source noteuspto-grants-2010_06