Hydrochloric Acid → HCID 69656099, compound

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Reaction Steps

A stirred solution of (2S,3R)-2-(N-t-butoxycarbonylamino)-3-methoxy-1-(3-quinolylmethanesulfonyl)butane (1 g) in MDC (10 ml) at rt was treated with 4M hydrogen chloride in dioxan (10 ml). After 1 h the mixture was evaporated to give the subtitle compound (0.93 g). MS (APCI+ve ion) 309 (MH+), 1H NMR δ(DMSO-d6) 9.04 (1H, m), 8.71 (1H, s), 8.3 (3H, broad s), 8.2 (2H, m), 7.91 (1H, t, J=8 Hz), 7.78 (1H, t, J=8 Hz), 5.08 (2H, m), 3.3–3.88 (4H, m), 3.31 (3H,s), 1.7 (2H, m), 1.19 (3H, d,J=6.3 Hz),

Provenance & Evidence