HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-3-pyridinecarbonitrile → 6-[(2-{[4-(4-Chloro-2-methoxyphenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}-ethyl)amino]pyridine-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-3-pyridinecarbonitrile | HCID 5152094 | — |
| Reactant | Chir-98023 | HCID 9847557 | — |
| Reactant | 4-Chloro-2-methoxybenzoyl chloride | HCID 22142450 | — |
| Product | 6-[(2-{[4-(4-Chloro-2-methoxyphenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}-ethyl)amino]pyridine-3-carbonitrile | HCID 22143066 | — |
Reaction Steps
6-[(2-{[4-(4-chloro-2-methoxyphenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile was prepared from 4-chloro-2-methoxybenzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037918B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-4acb191a6fb74efe96602896475b7d91 |
| Source note | uspto-grants-2006_05 |