HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2-chloropyrimidine-5-carbonitrile → 4-Amino-2-[(2-{[4-(4-cyanophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)-amino]pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2-chloropyrimidine-5-carbonitrile | HCID 2801166 | — |
| Reactant | 4-{5-Imidazolyl-2-[(2-{[5-(trifluoromethyl) (2-pyridyl)]amino}ethyl)amino]pyrimidin-4-yl}benzenecarbonitrile | HCID 57142481 | — |
| Product | 4-Amino-2-[(2-{[4-(4-cyanophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)-amino]pyrimidine-5-carbonitrile | HCID 22142472 | — |
Reaction Steps
4-amino-2-[(2-{[4-(4-cyanophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]pyrimidine-5-carbonitrile was prepared from 4-amino-2-chloropyrimidine-5-carbonitrile using the general method for 4-{5-imidazolyl-2-[(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amino]pyrimidin-4-yl}benzenecarbonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037918B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-cdee0b9c8d0b4545b2df512edf1729f9 |
| Source note | uspto-grants-2006_05 |