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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1823758Generated: November 1, 2026

Sodium Hydroxide → 4-(3-(2,6-Dimethylbenzyloxy)phenyl)-3-butenoic acid

https://huagongshe.com/reaction/1823758

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 69594363HCID 69594363—
SolventEthanolHCID 702—
Product4-(3-(2,6-Dimethylbenzyloxy)phenyl)-3-butenoic acidHCID 67273606—

Reaction Steps

To a solution of Ethyl 4-(3-(2,6-dimethylbenzyloxy)phenyl)-3-butenoic acid: ethanol at low temp, add aqueous sodium hydroxide, after an hour, concentrate and purify by flash chromatography on silica gel column (chloroform:methanol 95:5 spiked with acetic acid).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07041659B2
Source datasetuspto-grants-2006_05
ORD IDord-d5f47a26b9b4445c8185dfc0191171a6
Source noteuspto-grants-2006_05