1-Isocyanato-2-phenylbenzene → HCID 86593357, compound

HRID 1823799Notes

Reaction equation

HRID 1823799 reaction equation
[CH:1]1[CH:6]=[CH:5][C:4]([C:7]2[C:12]([N:13]=[C:14]=[O:15])=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:3][CH:2]=1.[C@@:16]12([OH:25])[N:23]([CH3:24])[C@@H:20]([CH2:21][CH2:22]1)[CH2:19][CH:18]=[CH:17]2>C(#N)C>[C:12]1([NH:13][C:14]([O:25][C@@:16]23[N:23]([CH3:24])[C@@H:20]([CH2:21][CH2:22]2)[CH2:19][CH:18]=[CH:17]3)=[O:15])[C:7]([C:4]2[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=2)=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 2222801-Isocyanato-2-phenylbenzeneHCID 53629842Tropenol

Product 1

HCID 86593357HCID 86593357, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent2×

Procedure

5.0 g (0.026 mol) of 2-biphenylisocyanate is placed in 10 mL acetonitrile, and a solution of 3.619 g (0.026 mol) tropenol in 5 mL acetonitrile is added dropwise, then stirred for 24 hours at ambient temperature. The solution is concentrated by evaporation and the residue is distributed between dichloromethane and water. The organic phase is dried over sodium sulfate and evaporated to dryness. Yield: 7.4 g yellowish-orange oil (85% of theory).

Workup

  1. concentrationThe solution is concentrated by evaporation
  2. dry with materialThe organic phase is dried over sodium sulfate
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-96f203e6ef484c85986a6b77d589fad1
Source dataset
uspto-grants-2006_05
Patent number
US07041674B2

Reaction notes

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