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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 182384Generated: October 31, 2026

Tetrahydrofuran → tert-Butyl 5-chloro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxylate

https://huagongshe.com/reaction/182384

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
Reactantethyl N-ethoxycarbonyliminocarbamateHCID 220568—
Reactanttert-Butyl 4-(4-chloro-2-(hydroxymethyl)phenyl)-4-hydroxypiperidine-1-carboxylateHCID 57889172—
Producttert-Butyl 5-chloro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxylateHCID 57889918—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6d41cd2ecfe641b0816a9e019a1f5940
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)