HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzamidine → 2-(4-chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzamidine | HCID 203437 | — |
| Reactant | 2-Bromo-1-(3-chloro-2-thienyl)-1-ethanone | HCID 2764498 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-(4-chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-1H-imidazole | HCID 22147873 | — |
Reaction Steps
Compounds of this invention with Formula IV may be prepared as illustrated by the exemplary reaction in Scheme 3. Reaction of 2-bromo-1-(3-chloro-thiophen-2-yl)-ethanone with 4-chloro-benzamidine in chloroform produces the product 2-(4-chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-1H-imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07041685B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-192882aa987643eea4938325bb67510b |
| Source note | uspto-grants-2006_05 |