3-Chlorothiophene-2-carbonyl chloride → HCID 22147918, compound
Reaction equation
[Cl:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[C:7](Cl)=O.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]([NH:19][NH2:20])=[NH:18])=[CH:13][CH:12]=1>>[Cl:10][C:11]1[CH:12]=[CH:13][C:14]([C:17]2[N:18]=[C:7]([C:3]3[S:4][CH:5]=[CH:6][C:2]=3[Cl:1])[NH:20][N:19]=2)=[CH:15][CH:16]=1Participants
3
Procedure
Compounds of this invention with Formula V may be prepared as illustrated by the exemplary reaction in Scheme 4. Reaction of 3-chloro-thiophene-2-carbonyl chloride with 4-chloro-benzenecarboximidic hydrazide produces the product 3-(4-chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-1H-[1,2,4]-triazole.
Workup
- customCompounds of this invention with Formula V may be prepared
- customas illustrated by the exemplary reaction in Scheme 4
Sources & evidence
- ORD record
- ord-9f9eaf56c2354295a91c2b45b3a85c77
- Source dataset
- uspto-grants-2006_05
- Patent number
- US07041685B2
Reaction notes
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