3-Pyridinecarbonyl chloride, hydrochloride (1:1) → HCID 22147877, compound

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Nicotinic acid N′-(3-chloro-thiophene-2-carbonyl)-hydrazide: The title compound was prepared from 3-chloro-thiophene-2-carbonyl hydrazide (70 mg, 0.40 mmol) and nicotinoyl chloride hydrochloride (348 mg, 1.96 mmol) similar to Example 84b, and yielded 76 mg (68%) of white solid. 1H NMR (DMSO-d6): 10.82 (s, 1H), 10.33 (s, 1H), 9.07 (s, 1H), 8.79 (d, J=3.84 Hz, 1H), 8.26 (d, J=6.87 Hz, 1H), 7.93 (d, J=5.22 Hz, 1H), 7.58 (dd, J=7.55, 4.53 Hz, 1H), 7.23 (d, J=4.95 Hz, 1H).

Provenance & Evidence