4-Chlorobenzoyl chloride → HCID 22147913, compound

Participants

Reaction Steps

N-[2-(3-Chloro-thiophen-2-yl)-2-oxo-ethyl]-4-chloro-benzamide: The title compound was prepared from 2-(3-chloro-thiophen-2-yl)-2-oxo-1-ethylamine hydrochloride (0.05 g, 0.235 mmol) and 4-chloro-benzoyl chloride (0.02 mL, 0.235 mmol) by a procedure similar to Example 97a to yield 0.048 g (72.7%) of white solid. 1H NMR (CD3OD): 7.77 (m, 3H), 7.43 (d, J=8.4 Hz, 2H), 7.36 (t, 1H), 7.05 (d, J=5.4 Hz, 1H), 4.75 (d, J=9.3 Hz, 2H).

Provenance & Evidence