Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate → HCID 23571082, compound

Participants

Reaction Steps

Prepared using [6S,9R,11R]2′,3′,4′,5,5′,6,7,8,9,10-Decahydro-2-(5-bromothiazol-2-yl)-5′-(2,2,2-trifluoroethyl)-spiro[6,9-methanobenzocyclooctene-11,3′-[1,2,5]thiadiazole]1′,1′-dioxide (prepared using the homochiral boronate from Example 24 Step 1 by the method described for Example 36 Steps 1–2) and the boronate from Example 39 Step 2 using the method described for Example 36 Step 3. MS (ES+) 625 ([MH]+); [α]D=−11 (c=0.62, DMSO, 23° C.).

Provenance & Evidence