4-(Trifluoromethyl)phenylboronic acid → HCID 23571170, compound

HRID 1823977Notes

Reaction equation

HRID 1823977 reaction equation
Br[C:2]1[S:6][C:5]([C:7]2[CH:8]=[CH:9][C:10]3[CH2:17][CH:16]4[C:18]5([CH2:22][N:21]([CH2:23][C:24]([F:27])([F:26])[F:25])[S:20](=[O:29])(=[O:28])[NH:19]5)[CH:13]([CH2:14][CH2:15]4)[CH2:12][C:11]=3[CH:30]=2)=[N:4][CH:3]=1.[F:31][C:32]([F:43])([F:42])[C:33]1[CH:38]=[CH:37][C:36](B(O)O)=[CH:35][CH:34]=1>>[F:31][C:32]([F:43])([F:42])[C:33]1[CH:38]=[CH:37][C:36]([C:2]2[S:6][C:5]([C:7]3[CH:8]=[CH:9][C:10]4[CH2:17][CH:16]5[C:18]6([CH2:22][N:21]([CH2:23][C:24]([F:27])([F:26])[F:25])[S:20](=[O:29])(=[O:28])[NH:19]6)[CH:13]([CH2:14][CH2:15]5)[CH2:12][C:11]=4[CH:30]=3)=[N:4][CH:3]=2)=[CH:35][CH:34]=1

Participants

3

Reactant 2

HCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 22147984HCID 22147984, compound

Product 1

HCID 23571170HCID 23571170, compound

Procedure

Prepared using the bromide from Example 36 Step 2 and 4-trifluoromethylbenzeneboronic acid by the method described for Example 36 Step 3. MS (ES+) 588 ([MH]+).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1c5318a2d1314b278165cdfec8eb1650
Source dataset
uspto-grants-2006_05
Patent number
US07041689B2

Reaction notes

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