4-Benzyloxyaniline hydrochloride → HCID 178479358, compound

Participants

Reaction Steps

Synthesis of this compound was achieved by the method set forth in Example 1, Part II above with the use of N-(2-thiophenecarbonyl)cyanamide in place of N-(4-methylbenzoylcyanamide) and using 4-benzylcyanamide and using 4-benzyloxyaniline hydrochloride instead of 4-isopropylaniline hydrochloride respectively. Yield 61%; m.p. 198–202° C.; Purity 93% (HPLC); 1H-NMR (CD3OD) δ 5.18 (s, 2H, CH2), 7.18 (d, 2H), 7.22–7.4 (m, 6H), 7.44 (d, 2H), 7.9 (d, 1H), 8.18 (d, 1H).

Provenance & Evidence