HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S,2R)-(-)-1-Amino-2-indanol → (1S,2R)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S,2R)-(-)-1-Amino-2-indanol | HCID 9866743 | — |
| Reactant | (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583341 | — |
| Product | (1S,2R)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583464 | — |
Reaction Steps
Following the procedure for the preparation of (1R,2S)-1-[(3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting (1S,2R)-(−)-cis-1-amino-2-indanol and making non-critical variations provided the title compound as a light purple solid. MS (ESI+) for C17H21N3O m/z 284.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07041672B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-899305b325a14b16aa5385366dd874e2 |
| Source note | uspto-grants-2006_05 |